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Iron During Pregnancy Possibly Harmful

 
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ironjustice
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PostPosted: Sat Mar 01, 2008 2:54 am    Post subject: Iron During Pregnancy Possibly Harmful Reply with quote

Evidence-Based Medicine
2008;13:15; doi:10.1136/ebm.13.1.15
Copyright (c) 2008 by the BMJ Publishing Group Ltd.
--------------------------------------------------------------------------------

THERAPEUTICS

Iron supplementation in non-anaemic women did not improve pregnancy
outcomes and may be harmful to both mother and baby

S Ziaei

Dr S Ziaei, Tarbiat Modarres University, Tehran, Iran;
ziaei_99@yahoo.com


STUDY DESIGN

Design:
randomised placebo-controlled trial.

Allocation:
unclear.*

Blinding:
blinded (patients and healthcare providers).*


STUDY QUESTION

Setting:
6 prenatal clinics in Iran.

Patients:
750 non-smoking women 17-35 years of age (mean age 26 y) with a
singleton pregnancy in the early second trimester (mean 13 wks),
haemoglobin concentration 13.2 (mean 14.0) g/dl, body mass index 19.8-
26 kg/m2, no history of threatened abortion in the current pregnancy,
and no disease related to polycythaemia such as asthma or chronic
hypertension.

Intervention:
ferrous sulphate, 150 mg (50 mg of elemental iron) (n = 375), or
placebo (n = 375) once daily throughout pregnancy. All women received
folic acid, 1 mg/day, but were not allowed to take other vitamin or
mineral supplements.

Outcomes:
small for gestational age (SGA, <10th percentile) infant, hypertensive
disorder, premature labour, caesarean delivery for obstetrical
reasons, Apgar score, birthweight, and perinatal mortality.

Follow-up period:
6 weeks after delivery.

Patient follow-up:
97% (intention-to-treat analysis). . . . [Full text of this article]

Claudio Giorlandino

Pietro Cignini

Artemisia Prenatal Diagnosis Centre, Rome, Italy


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ironjustice
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PostPosted: Sun Mar 02, 2008 2:20 pm    Post subject: Re: Iron During Pregnancy Possibly Harmful Reply with quote

On Feb 29, 6:54 pm, ironjustice <teamtan...@hotmail.com> wrote: Iron
supplementation in non-anaemic women did not improve pregnancyoutcomes
and may be harmful to both mother and baby <<

http://tinyurl.com/5ccke

Via prenatal vitamins, over the course of just 7 months, women could
be getting close to an additional 5 grams to almost 20 GRAMS of iron -
depending on the brand of prenatal vitamins used given prenatal
vitamins could provide doses of iron of up to 90 mg/day [22].


Who loves ya.
Tom


Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com


Man Is A Herbivore!
http://tinyurl.com/a3cc3


DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk





Quote:
Evidence-Based Medicine
2008;13:15; doi:10.1136/ebm.13.1.15
Copyright (c) 2008 by the BMJ Publishing Group Ltd.
---------------------------------------------------------------------------­-----

THERAPEUTICS

Iron supplementation in non-anaemic women did not improve pregnancy
outcomes and may be harmful to both mother and baby

S Ziaei

Dr S Ziaei, Tarbiat Modarres University, Tehran, Iran;
ziaei...@yahoo.com

    STUDY DESIGN

Design:
randomised placebo-controlled trial.

Allocation:
unclear.*

Blinding:
blinded (patients and healthcare providers).*

    STUDY QUESTION

Setting:
6 prenatal clinics in Iran.

Patients:
750 non-smoking women 17-35 years of age (mean age 26 y) with a
singleton pregnancy in the early second trimester (mean 13 wks),
haemoglobin concentration 13.2 (mean 14.0) g/dl, body mass index 19.8-
26 kg/m2, no history of threatened abortion in the current pregnancy,
and no disease related to polycythaemia such as asthma or chronic
hypertension.

Intervention:
ferrous sulphate, 150 mg (50 mg of elemental iron) (n = 375), or
placebo (n = 375) once daily throughout pregnancy. All women received
folic acid, 1 mg/day, but were not allowed to take other vitamin or
mineral supplements.

Outcomes:
small for gestational age (SGA, <10th percentile) infant, hypertensive
disorder, premature labour, caesarean delivery for obstetrical
reasons, Apgar score, birthweight, and perinatal mortality.

Follow-up period:
6 weeks after delivery.

Patient follow-up:
97% (intention-to-treat analysis). . . . [Full text of this article]

Claudio Giorlandino

Pietro Cignini

Artemisia Prenatal Diagnosis Centre, Rome, Italy

Who loves ya.
Tom

Jesus Was A Vegetarian!http://jesuswasavegetarian.7h.com

Man Is A Herbivore!http://tinyurl.com/a3cc3

DEAD PEOPLE WALKINGhttp://tinyurl.com/zk9fk
Back to top
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